Enhancing Prime Editing: The Pivotal Role of La Protein in RNA Stabilization and Genome Accuracy

How the La Protein Revolutionizes CRISPR’s Prime Editing Efficiency and Unlocks Genetic Precision

7 mins
What is it about?

Biology

Chemistry

Technology

Prime editing is an advanced genome-editing technique derived from CRISPR technology, which allows precise modifications in the genome with minimal unwanted side effects. It employs a "prime editor" protein linked with a prime editing guide RNA (pegRNA) that dictates both the DNA target site and the specific edit to be made. This system is recognized for its accuracy and versatility, making it valuable in areas like genetic research, medicine development, and more.